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Effect of contact lens driven deformations on ocular health

About one in ten Americans wears contact lenses, however discomfort and dryness are the main reasons why individuals stop wearing contact lenses. To study contact lens discomfort, we investigate the interactions between the contact lens and the eye. We propose a mathematical model to quantify the deformability of the eye when a contact lens is inserted onto [Read More...]

Presenter: Kara Maki, Rochester Institute of Technology
Authors: Lucia Carichino, Kara L. Maki, and David S. Ross
Symposium Year: 2022
Session: Mathematical Modeling of the Eye: A Window to Our Health
Presentation Time: June 17, 2022; 3:30 pm

From the blackboard to the clinic: combining mechanism-driven models with artificial intelligence for individualized medicine in ophthalmology*

Artificial Intelligence (AI) aims at extracting information and knowledge from data. AI is naturally interdisciplinary, as it bridges fundamental techniques of data analysis, typically developed by mathematicians, statisticians and computer scientists, with the needs of actionable insights that are specific to the particular application domain. [Read More...]

Presenter: Giovanna Guidoboni, University of Missouri
Authors: Giovanna Guidoboni, James Keller, Chris Wikle, Erin Robinson, Robert Nunez, Daphne Zou, Rajat Rai, Aaron Beckwith, Maggie Lin, Alice Chandra Verticchio Vercellin, Brent Siesky, Alon Harris
Symposium Year: 2022
Session: Mathematical Modeling of the Eye: A Window to Our Health
Presentation Time: June 17, 2022; 3:55 pm

Spreading Mechanics and Differentiation of Astrocytes During Retinal Development

In embryonic development, formation of the retinal vasculature is critically dependent on prior establishment of a mesh of astrocytes. Astrocytes emerge from the optic nerve head and then migrate over the retinal surface in a radially symmetric manner and mature through differentiation. We develop a PDE model describing the migration and differentiation of [Read More...]

Presenter: Tracy L. Stepien, University of Florida
Authors: Tracy L. Stepien, Timothy W. Secomb
Symposium Year: 2022
Session: Mathematical Modeling of the Eye: A Window to Our Health
Presentation Time: June 17, 2022; 4:20 pm

Parameter Identification for Tear Film Thinning and Breakup

Dry eye disease is caused by a breakdown of a uniform tear film, which occurs when the layer of tears experiences breakup. To better understand this ocular condition, the dynamics of the tear film can be studied using fluorescence imaging. Many parameters affect tear film thickness and fluorescent intensity distributions over time; exact values or ranges [Read More...]

Presenter: Rayanne Luke, Johns Hopkins University, National Institute of Standards and Technology
Authors: Rayanne A. Luke, Richard J. Braun, Tobin A. Driscoll, Carolyn G. Begley, Deborah Awisi-Gyau
Symposium Year: 2022
Session: Mathematical Modeling of the Eye: A Window to Our Health
Presentation Time: June 17, 2022; 4:45 pm

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